Peptides are short chains of amino acids that act as signaling molecules in the body — directing biological processes like tissue repair, growth hormone release, immune response, metabolism, and more. Peptide therapy uses modified or synthetic versions of these compounds to target specific wellness goals with precision.
At MD Total Wellness in Brea, CA, every care plan is personalized around what will have the biggest impact for you. For some patients, that means starting with peptide therapy — Wolverine blend for accelerated healing after an injury, GHK-Cu for skin and hair health, or Sermorelin for growth hormone support. For others, TRT, hormone therapy, or GLP-1 weight loss will have the broadest initial impact, with peptides added to target specific concerns. Our board-certified providers work with you to determine the right starting point and build from there.
Because peptides interact with your body’s existing hormonal and metabolic environment, physician oversight matters. Every peptide protocol at MDTW is designed by a board-certified provider based on your health history, current treatments, and specific goals — not a one-size-fits-all approach.
For a full overview of our peptide program, pricing, and how to get started, visit our Peptide & NAD+ Therapy service page.
The following sections organize the peptides we offer by primary wellness goal. Many peptides appear in more than one category — reflecting their broad biological activity. Where combinations are particularly effective, we note the synergistic protocols we use at MDTW.
For patients recovering from injury, surgery, or physical strain, peptide therapy can significantly accelerate the healing process by stimulating the body’s own repair mechanisms.
Wolverine Blend (BPC-157 / TB-500) — Our most popular peptide offering. BPC-157 and TB-500 work synergistically — increasing blood flow to injury sites, aggregating and activating repair cells, and reducing inflammation and scarring. Ideal for tendon, ligament, muscle, and joint injuries, post-surgical recovery, and chronic inflammation. Most patients see results within 1-4 weeks. We offer the Wolverine blend as a combined formulation, or BPC-157 and TB-500 individually for patients whose providers recommend separating them. Learn more about Wolverine Blend →
BPC-157 (Body Protection Compound-157) — Available individually for patients who benefit specifically from its local tissue repair, gut health, and angiogenesis effects without TB-500. Particularly useful for gut-related inflammation and localized musculoskeletal injuries.
TB-500 (Thymosin Beta-4 Acetate) — Available individually for patients who benefit specifically from its systemic cell migration, wound healing, and anti-inflammatory effects. TB-500 has a more systemic distribution pattern than BPC-157, making it useful when broader tissue repair is the goal.
GLOW Blend — A combination of BPC-157, TB-500, and GHK-Cu — combining the healing and recovery benefits of the Wolverine blend with the skin, hair, and anti-aging properties of GHK-Cu. Ideal for patients seeking both tissue repair and regenerative skin and hair benefits in a single protocol. Learn more about GLOW Blend →
KLOW Blend — The same formulation as GLOW (BPC-157, TB-500, GHK-Cu) with the addition of KPV for enhanced anti-inflammatory and gut-healing effects. Particularly useful for patients with inflammatory gut conditions alongside healing and recovery goals. Learn more about KLOW Blend →
KPV — A tripeptide fragment with potent anti-inflammatory and gut-healing properties. KPV is particularly useful for patients with inflammatory gut conditions such as IBD, IBS, or leaky gut — reducing intestinal inflammation and supporting mucosal healing.
Chronic low-grade inflammation underlies many of the conditions we treat at MDTW — from joint pain and slow recovery to metabolic dysfunction and accelerated aging. Several peptides have significant anti-inflammatory activity:
KPV — Potent gut and systemic anti-inflammatory. Particularly effective for gut-related inflammation.
BPC-157 — Reduces inflammatory cytokines locally at injury sites. One of the most studied peptides for inflammation-driven musculoskeletal conditions.
GHK-Cu — Broad anti-inflammatory and antioxidant effects, with gene-level suppression of inflammatory pathways. Useful for chronic systemic inflammation, skin inflammation, and joint health.
TB-500 — Reduces inflammation and scarring at injury sites through cell migration and activation of repair pathways.
KLOW Blend — Combines the anti-inflammatory effects of KPV with BPC-157, TB-500, and GHK-Cu for a comprehensive healing, recovery, and anti-inflammatory protocol in a single blend.
Many MDTW patients who are already on TRT, BHT, or GLP-1 weight loss benefit from adding anti-inflammatory peptides as a targeted layer — particularly those experiencing joint pain, slow recovery, or gut issues alongside their primary treatment.
Growth hormone (GH) declines naturally with age — contributing to reduced muscle mass, increased fat, lower energy, and slower metabolism. Growth hormone-releasing peptides stimulate the pituitary gland to increase GH production through the body’s own pathways, offering a safer and more physiologic alternative to direct GH administration.
Sermorelin – A GHRH analog that stimulates the pituitary to produce and release growth hormone. Previously FDA-approved for GH deficiency in children — discontinued for economic, not safety, reasons. Used off-label for age-related GH decline. Benefits include increased energy, improved body composition, better sleep quality, and faster exercise recovery. Can be used as a standalone treatment or combined with hormone therapy. [Learn more about Sermorelin →]
Tesamorelin – A potent GHRH analog FDA-approved for reducing visceral fat in HIV-associated lipodystrophy — used off-label for visceral fat reduction and metabolic health. Particularly useful for patients with stubborn abdominal fat who are already on a GLP-1 program. [Learn more about Tesamorelin →]
Ipamorelin – A selective growth hormone secretagogue that stimulates GH release with minimal effect on cortisol or prolactin — making it one of the cleanest GH-stimulating peptides available. Frequently used in combination with Tesamorelin and CJC-1295 for a synergistic protocol.
Tesamorelin / Ipamorelin Stack – Combines Tesamorelin’s visceral fat reduction with Ipamorelin’s clean GH stimulation — a powerful combination for patients focused on body composition and metabolic health.
CJC-1295 – A longer-acting GHRH analog that produces sustained elevation of GH and IGF-1 levels. Often combined with Ipamorelin for enhanced effect.
CJC-1295 / Ipamorelin Stack – Combines CJC-1295’s sustained GH elevation with Ipamorelin’s clean, selective stimulation. Particularly effective for body composition improvement, metabolic support, and recovery.
MOTS-c A mitochondria-derived peptide that improves insulin sensitivity, supports metabolic flexibility, and enhances cellular energy production. Particularly useful for patients with metabolic syndrome, insulin resistance, or those seeking to enhance the metabolic benefits of their GLP-1 program.
GH-stimulating peptides complement our GLP-1 weight loss program by preserving muscle mass and supporting metabolic health during weight loss — a common concern for patients on semaglutide or tirzepatide.
Several peptides at MDTW target the biological mechanisms of aging — at the cellular, genetic, and hormonal level.
GHK-Cu – Declines by approximately 60% by age 60, contributing to reduced skin elasticity, hair thinning, and slower tissue repair. GHK-Cu influences over 4,000 genes, acting as an epigenetic modifier that reverses age-related gene expression — suppressing inflammatory genes and activating tissue regeneration pathways. Learn more about GHK-Cu →
NAD+ – NAD+ is a coenzyme essential for cellular energy production and DNA repair, declining significantly with age. NAD+ therapy replenishes these levels, activating sirtuins (proteins linked to longevity), improving mitochondrial function, and combating fatigue. Many patients notice improved energy and mental clarity within days.
Epitalon – A tetrapeptide that activates telomerase — the enzyme responsible for maintaining telomere length, a key marker of cellular aging. Epitalon is studied for its role in extending cellular lifespan, improving sleep quality, and supporting hormonal regulation in aging.
MOTS-c – Beyond its metabolic effects, MOTS-c supports cellular longevity through mitochondrial health and stress resistance — making it a useful addition to anti-aging protocols.
GLOW & KLOW Blends GLOW combines BPC-157, TB-500, and GHK-Cu for comprehensive tissue repair and skin regeneration. KLOW adds KPV for patients who also need anti-inflammatory gut support. Both blends are particularly useful for patients seeking anti-aging benefits alongside healing and recovery.
Anti-aging peptides work most effectively alongside optimized hormone levels. Patients on our bioidentical hormone therapy or testosterone therapy programs often layer in anti-aging peptides for enhanced results.
Several peptides at MDTW have significant benefits for skin rejuvenation, hair restoration, and overall integumentary health.
GHK-Cu The most versatile skin and hair peptide we offer. Stimulates collagen, elastin, and hyaluronic acid production; activates hair follicles; reduces inflammation; and reverses age-related gene expression in skin cells. Learn more about GHK-Cu →
Wolverine Blend / BPC-157 Promotes new blood vessel growth and collagen production — useful for patients recovering from aesthetic procedures or with wounds requiring enhanced healing.
GLOW Blend Combines BPC-157, TB-500, and GHK-Cu — adding the collagen-stimulating and anti-aging skin benefits of GHK-Cu to the tissue repair effects of the Wolverine blend.
KLOW Blend Adds KPV’s anti-inflammatory effects to the GLOW formula — particularly beneficial for patients with inflammatory skin conditions like acne, rosacea, or eczema alongside their skin rejuvenation goals.
At MDTW, GHK-Cu is a core component of our hair restoration program — typically combined with the Alma TED system, low-level laser therapy, and DHT-blocking medications for a comprehensive multimodal approach. Hair loss from GLP-1 medications or hormone changes is a common concern we see and treat effectively.
NAD+ Improves mitochondrial function and cellular energy in neurons — supporting mental clarity, focus, and resilience against cognitive decline. Many patients notice improved mental energy within days of starting NAD+ therapy.
Selank A synthetic analog of the immune peptide tuftsin with anxiolytic (anti-anxiety) and nootropic effects. Selank reduces anxiety, improves focus, and supports emotional stability without sedation or dependency.
Semax A neuropeptide that increases BDNF (brain-derived neurotrophic factor), supporting neuronal growth and cognitive performance. Used for improved focus, memory, and mental clarity.
DSIP (Delta Sleep-Inducing Peptide) A neuropeptide that promotes deep, restorative sleep by modulating sleep-wake cycles. Useful for patients with chronic sleep disruption — particularly relevant for patients on hormone therapy where sleep quality is a common concern.
Cognitive and mood peptides often complement hormone therapy — low testosterone and estrogen deficiency both independently affect cognition and mood, and peptides can provide additional targeted support.
PT-141 (Bremelanotide) FDA-approved for hypoactive sexual desire disorder (HSDD) in women, and used off-label for libido enhancement and erectile dysfunction in both men and women. Unlike traditional ED treatments that target blood flow, PT-141 works centrally — activating melanocortin receptors in the brain to enhance desire and arousal. Particularly useful when psychological or neurological factors contribute to sexual health challenges.Â
Sexual health peptides work best alongside optimized hormone levels. Patients on testosterone therapy or bioidentical hormone therapy often find that PT-141 provides additional benefit — addressing desire and arousal at the neurological level while hormone therapy addresses the underlying hormonal foundation.
One of MDTW’s key advantages is that we treat the whole patient — not just a single condition. One of MDTW’s key advantages is that we treat the whole patient — not just a single condition. Many patients come to us specifically for peptides, and many others add peptides to an existing GLP-1 or hormone therapy plan. Either way, here are common combinations that produce particularly strong results:
GLP-1 + Body Composition Peptides — Patients on semaglutide or tirzepatide commonly add Sermorelin, Tesamorelin, or Tesamorelin/Ipamorelin to preserve muscle mass and support metabolic health during weight loss.
Testosterone Therapy + Recovery Peptides — Men on TRT often benefit from adding Wolverine blend or BPC-157 for enhanced recovery, joint health, and healing.
GLP-1 + Hair Restoration Peptides — Hair loss is a common side effect of rapid weight loss on GLP-1 medications. GHK-Cu, combined with Alma TED and other hair restoration treatments, directly addresses this.
Hormone Therapy + Anti-Aging Peptides — Women on bioidentical hormone therapy frequently add GHK-Cu, NAD+, or Epitalon for skin, hair, energy, and longevity benefits.
Hormone Therapy + Sexual Health Peptides — PT-141 complements both TRT and women’s hormone therapy by addressing the neurological dimension of sexual health.
A 15-minute consultation ($100) with one of our board-certified providers — in person or via telehealth — covers your full evaluation, personalized protocol, and usage instructions. The $100 fee is applied toward your peptide purchase if you proceed. Active MDTW patients currently enrolled in monthly GLP-1 or hormone therapy programs receive the consultation at no charge — new patients pay $100, applied toward their first peptide purchase.
Visit our Peptide & NAD+ Therapy service page for full program details and pricing, or call us at 714-671-2005 or contact us online to get started.
Work with our medical team to build a personalized care plan.
Relieve perimenopause and menopause symptoms with our menopause-certified provider.
Restore energy, strength, and vitality by treating low testosterone.
Strengthen the pelvic floor to treat incontinence and improve intimate wellness.
Treat dryness, laxity, and painful or unsatisfying sex with Emfemme — non-invasive and effective.
